The GPER1 Rabbit Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to GPER1. This antibody recognizes Human, Mouse, and Rat antigen. The GPER1 Rabbit Polyclonal Antibody has been validated for the following applications: Immunohistochemistry, and Western Blot.
Description
This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized